目的 对一年蓬的化学成分进行分离和结构鉴定。方法 运用Diaion HP-20、Toyopearl HW-40、Sephadex LH-20、硅胶、制备液相等多种柱色谱技术进行分离纯化,并根据化合物的光谱数据和理化性质进行结构鉴定。结果 分离得到20个化合物,分别为香草酸(1),阿魏酸(2),对羟基苯乙酮(3),二氢松柏醇(4),黑麦草内酯(5),4-羟基-3-甲氧基苯丙-8-烯-4-O-β-D-吡喃木糖基-(1→6)-β-D-吡喃葡萄糖苷(6),吲哚-3-甲醛(7),5,7-二羟基色原酮(8),焦袂康酸(9),erigeside D(10),3,5-二甲氧基-4-O-(β-D-吡喃葡萄糖基)-苯甲酸甲酯(11),二氢去氢二愈创木基醇-4′-O-β-D-葡萄糖苷(12),高圣草素(13),二氢高良姜醇(14),白杨素(15),高车前素(16),金圣草素(17),环桑皮素(18),蓟黄素(19)和柚皮素(20)。结论 化合物1~8、11~19为首次从该植物中分到。
Abstract
OBJECTIVE To study the chemical constituents of Erigeron annuus (L.) Pers.. METHODS The compounds were isolated and purified by Diaion HP-20, Toyopearl HW-40, Sephadex LH-20, MCI Gel CHP-20, silica gel column chromatography, and preparative HPLC, and their structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS Twenty compounds were elucidated as vanillic acid(1), ferulic acid(2), 4-hydroxyacetophenone(3), dihydroconiferylalcohol(4), loliolide(5), 4-hydroxy-3-methoxyphenylprop-8-ene 4-O-β-D-xylopyraosyl-(1→6)-β-D-glucopyranoside(6), 1H-indole-3-carbaldehyde(7), 5,7-dihydroxychromone(8), pyromeconic acid(9), erigeside D(10), methyl syringate 4-O-β-D-glucopyranoside(11),(7S,8R)-urolignoside(12), homoeriodictyol(13), pinobaksin(14), chrysin(15), hispidulin(16), chryseriol(17), cyclomorusin(18), cirsimaritin(19), and naringenin(20), respectively. CONCLUSION Compounds 1-8 and 11-19 is isolated from this plant for the first time.
关键词
一年蓬 /
酚酸 /
吡喃酮 /
黄酮
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Key words
Erigeron annuus (L.) Pers. /
phenolic acid /
pyrone /
flavonoid
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中图分类号：
R284
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参考文献
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脚注
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基金
教育部科学技术研究重点资助项目(DF2003078)
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